Pyoderma gangrenosum followed by subcorneal pustular dermatosis in a patient with IgA paraproteinemia

J Am Acad Dermatol. 1991 Feb;24(2 Pt 2):325-8. doi: 10.1016/0190-9622(91)70043-2.


Six months after the occurrence of pyoderma gangrenosum, subcorneal pustular dermatosis developed in a 60-year-old woman. The patient's serum was found to contain an IgA-lambda paraprotein. Although similar cases have been reported, this case is unique in that a distinct episode of pyoderma gangrenosum was followed by subcorneal pustular dermatosis.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Gangrene
  • Humans
  • Hypergammaglobulinemia / complications*
  • Immunoglobulin A*
  • Middle Aged
  • Pyoderma / complications*
  • Pyoderma / pathology
  • Skin / pathology
  • Skin Diseases, Vesiculobullous / complications*
  • Skin Diseases, Vesiculobullous / pathology


  • Immunoglobulin A