Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 80 (12), 1472

FPIN's Clinical Inquiries. Aspirin Use in Children for Fever or Viral Syndromes

Affiliations
  • PMID: 20000310

FPIN's Clinical Inquiries. Aspirin Use in Children for Fever or Viral Syndromes

Anthony I Beutler et al. Am Fam Physician.

Abstract

Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case-control studies). Although no causal link has been proven, data from case-control and historic cohort studies demonstrate an association between aspirin use and Reye syndrome. The risk of Reye syndrome decreases with age, becoming extremely rare by the late teenage years. Other nonsteroidal anti-inflammatory drugs are effective antipyretics and are not associated with the constellation of symptoms seen in Reye syndrome, which includes nausea, vomiting, headache, excitability, delirium, combativeness, and coma. Aspirin use in children younger than 19 years should be limited to diseases in which aspirin has a proven benefit, such as Kawasaki disease and the juvenile arthritides. (SOR: C, based on expert opinion).

Similar articles

See all similar articles

Cited by 1 article

Substances

Feedback