Evaluation of sleep quality in patients with refractory seizures who undergo epilepsy surgery

Epilepsy Behav. 2010 Jan;17(1):120-3. doi: 10.1016/j.yebeh.2009.11.008. Epub 2009 Dec 9.


The aim of the study was to evaluate excessive daytime sleepiness and subjective sleep quality in patients who undergo epilepsy surgery for treatment of refractory partial seizures. Forty-eight patients were enrolled in this research study. All of them were evaluated 2 days before and 3 months after the surgery. Two questionnaires were used to assess daytime sleepiness (Epworth Sleepiness Scale [ESS]) and sleep quality (Pittsburgh Sleep Quality Index [PSQI]). Global PSQI was high (mean=5.65 SD=3.71) before the surgical procedure (P<0.001). PSQI evaluation revealed higher and statistically significant scores in three components as well as in the global score, when analyzed by predominance of daytime or nocturnal seizures. ESS and PSQI scores were also analyzed by gender, antiepileptic drug class, age, and seizure frequency, with no significant differences. We concluded that patients with partial recurrent seizures of temporal origin have poor subjective sleep quality that improves significantly after epilepsy surgery.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Electroencephalography
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neurosurgical Procedures / methods*
  • Reaction Time / physiology
  • Retrospective Studies
  • Seizures / complications*
  • Seizures / surgery
  • Severity of Illness Index
  • Sleep Wake Disorders* / diagnosis
  • Sleep Wake Disorders* / etiology
  • Sleep Wake Disorders* / surgery
  • Statistics, Nonparametric
  • Surveys and Questionnaires
  • Treatment Outcome
  • Young Adult