Prolonged time to pregnancy is associated with a greater risk of adverse outcomes

Fertil Steril. 2010 Aug;94(3):1148-51. doi: 10.1016/j.fertnstert.2009.10.058. Epub 2009 Dec 11.


Births with known time to pregnancy (TTP) during the period 1989-2007 (n=17,114) were analyzed to investigate associations between TTP and pregnancy outcome among couples that conceived spontaneously. The adjusted odds ratio (95% confidence interval) for poor neonatal health, including low Apgar score, low umbilical vein pH, and need for neonatal intensive care, was 1.51 (1.09-2.09) in women who had a TTP of 25-36 months and 1.60 (1.18-2.19) in women who had a TTP of >or=37 months compared with women with a TTP of 0-6 months.

MeSH terms

  • Apgar Score
  • Birth Weight / physiology
  • Female
  • Fertility / physiology
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology
  • Pregnancy
  • Pregnancy Complications / epidemiology
  • Pregnancy Outcome / epidemiology*
  • Regression Analysis
  • Reproductive Techniques, Assisted / statistics & numerical data
  • Risk
  • Surveys and Questionnaires
  • Time Factors