The origin of renal fibroblasts and progression of kidney disease

Am J Pathol. 2010 Jan;176(1):22-4. doi: 10.2353/ajpath.2010.090898. Epub 2009 Dec 11.

Abstract

The Commentary highlights the article by Humphreys et al, “Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis” discussing hypothesis of renal progression.

Publication types

  • Comment

MeSH terms

  • Animals
  • Disease Models, Animal
  • Disease Progression*
  • Epithelial Cells / metabolism
  • Epithelial Cells / pathology
  • Epithelium / metabolism
  • Epithelium / pathology
  • Fibroblasts / metabolism
  • Fibroblasts / pathology*
  • Kidney / pathology*
  • Kidney Diseases / pathology*
  • Mesoderm / metabolism
  • Mesoderm / pathology
  • Mice