Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 11 (5), 497-8

Impaired Sleep Quality in Fibromyalgia: Detection and Quantification With ECG-based Cardiopulmonary Coupling Spectrograms

Impaired Sleep Quality in Fibromyalgia: Detection and Quantification With ECG-based Cardiopulmonary Coupling Spectrograms

Robert Joseph Thomas et al. Sleep Med.

Conflict of interest statement

Conflict of Interest

The following authors have a conflict of interest: Robert Joseph Thomas, M.D., Joseph E. Mietus, B.S., Chung-Kang Peng, Ph.D. and Ary L. Goldberger, M.D. They are all co-inventors of the sleep spectrogram technique, which is patented and licensed to Embla, Inc by the Beth Israel Deaconess Medical Center. All listed are covered by formal institutional royalty sharing properties. The payments in the past year have been less than $ 10,000. CKP is co-owner of DynaDx, Inc, a firm dedicated to the development of dynamic physiological assessments tools. ALG and JEM are consultants to DynaDx. None of the other authors have a relevant conflict of interest.

Figures

Figure
Figure. Sleep spectrogram in a healthy (left) and a fibromyalgia (right) subject
Note the dominance of high frequency coupling, which occurs periodically across the entire night in the healthy subject. This finding is distinct from slow wave sleep or delta power distributions, which are concentrated in the first half of the night. Note the paucity of time spent in high frequency coupling in the fibromyalgia patient. On the Y axis is plotted the log frequency representation of the coupling frequencies to allow differentiation of high frequency (HF), low frequency (LF) and very low frequency (VLF) bands; elevated-LFC is a subset of LFC. VLFC periods correlate with wake, REM or sleep-wake transitions.

Similar articles

See all similar articles

Cited by 16 PubMed Central articles

See all "Cited by" articles

Publication types

Feedback