Conductive keratoplasty followed by collagen cross-linking with riboflavin-UV-A in patients with keratoconus

Cornea. 2010 Feb;29(2):239-43. doi: 10.1097/ICO.0b013e3181a818ab.

Abstract

Purpose: To evaluate the combined effect of conductive keratoplasty (CK) followed by corneal collagen cross-linking (CXL) in 2 patients with keratoconus.

Methods: CK spots were applied on the flatter side of the cornea followed by CXL using riboflavin and UV-A light.

Results: Immediately after CK, a significant corneal topographic improvement was observed. The CK effect regressed 3 months postoperatively and remained unchanged until the sixth postoperative month in both patients.

Conclusion: Corneal remodeling with CK in patients with keratoconus seems to have a temporary effect despite the subsequent application of CXL.

Publication types

  • Case Reports

MeSH terms

  • Collagen / metabolism*
  • Combined Modality Therapy
  • Corneal Stroma / metabolism
  • Corneal Topography
  • Electrocoagulation*
  • Humans
  • Keratoconus / metabolism
  • Keratoconus / physiopathology
  • Keratoconus / therapy*
  • Male
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Riboflavin / therapeutic use*
  • Ultraviolet Rays
  • Visual Acuity / physiology
  • Young Adult

Substances

  • Photosensitizing Agents
  • Collagen
  • Riboflavin