Do wheezy infants recovering from bronchiolitis respond to inhaled salbutamol?

Pediatr Pulmonol. 1991;10(1):36-9. doi: 10.1002/ppul.1950100108.


Wheezy infants, less than 6 months of age, were given either inhaled salbutamol or saline in a double-blind study. A significant change in maximal flow at functional residual capacity (VmaxFRC) was defined as being greater than twice the coefficient of variation of the baseline measurements. There was no difference in the infants' response to saline or salbutamol. Wheezy infants, less than 6 months of age, do not have an increase in VmaxFRC following a single dose of inhaled salbutamol.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Albuterol / administration & dosage*
  • Albuterol / therapeutic use
  • Bronchiolitis, Viral / drug therapy*
  • Bronchiolitis, Viral / physiopathology
  • Double-Blind Method
  • Functional Residual Capacity / drug effects
  • Humans
  • Infant
  • Nebulizers and Vaporizers
  • Respiratory Sounds / drug effects*


  • Albuterol