Post stroke depression: treatments and complications in a young adult

Psychiatr Q. 2010 Mar;81(1):73-9. doi: 10.1007/s11126-009-9120-8.


Post-stroke depression has been noted to be one of the most frequent complications of stroke with an estimated prevalence of as high as 80%. However, the incidence of stroke in the young is extremely low and evidence based therapy for this complication is quite limited. The case of a 28-year-old woman who experienced a basilar artery vasospasmic stroke resulting in anoxic brain injury to the midbrain and paramedian thalamus is presented, along with a literature review of psychiatric complications of this injury to include post-stroke depression (PSD). Therapeutic modalities such as TCAs, SSRIs, atypical antipsychotics and stimulant medications are also reviewed as these medications may aid in the treatment of such patients but may also contribute to psychiatric sequelae.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antidepressive Agents / therapeutic use*
  • Antipsychotic Agents / therapeutic use*
  • Basilar Artery / physiopathology
  • Central Nervous System Stimulants / therapeutic use*
  • Depression / drug therapy*
  • Depression / etiology*
  • Depression / physiopathology
  • Depression / psychology
  • Female
  • Humans
  • Hypoxia, Brain / complications
  • Mesencephalon / pathology
  • Stroke / complications*
  • Thalamus / pathology
  • Vasospasm, Intracranial / complications


  • Antidepressive Agents
  • Antipsychotic Agents
  • Central Nervous System Stimulants