Mild fetal lateral cerebral ventriculomegaly: clinical course and outcome

Am J Obstet Gynecol. 1991 Mar;164(3):863-7. doi: 10.1016/0002-9378(91)90530-5.


The neonatal, pathologic outcome and karyotypic abnormalities are reported for 44 fetuses with mild ventriculomegaly diagnosed antenatally. Seventeen of these 44 fetuses (39%) had other ultrasonographic defects, and five (12%) had abnormal karyotypes. Five pregnancies were electively aborted and three other fetuses died in the neonatal period. Twenty-six (72%) of the remaining 36 live-born neonates are developmentally and clinically normal at 3 to 18 months of age. Twenty-one of these 26 had isolated mild ventriculomegaly as the only ultrasonographic finding. The other 10 live-born infants are developmentally impaired, and five of these 10 had mild ventriculomegaly as the only prenatal ultrasonographic abnormality. In conclusion, these data show that fetuses with mild ventriculomegaly have a lower incidence of associated anomalies and a better outcome than fetuses with more severe ventricular dilatation, as reported in the literature. The majority of fetuses with mild ventriculomegaly as an isolated finding and a normal karyotype are developing normally.

MeSH terms

  • Abnormalities, Multiple
  • Cerebral Ventricles / abnormalities*
  • Female
  • Humans
  • Karyotyping
  • Pregnancy
  • Prognosis
  • Ultrasonography, Prenatal