Abstract
Four new lanostane triterpenes, butyl ganoderate A (1), butyl ganoderate B (2), butyl lucidenate N (3), and butyl lucidenate A (4), were isolated from the fruiting bodies of Ganoderma lucidum together with 14 known compounds (5-18). The structures of the new triterpenes were established by extensive spectroscopic studies and chemical evidence. In addition, the inhibitory effect of isolated compounds on adipocyte differentiation in 3T3-L1 cells was examined.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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3T3-L1 Cells
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Adipocytes / drug effects
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Adipocytes / metabolism*
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Animals
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Fruiting Bodies, Fungal / chemistry
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Japan
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Lanosterol / analogs & derivatives*
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Lanosterol / chemistry
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Lanosterol / isolation & purification*
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Lanosterol / pharmacology*
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Mice
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Reishi / chemistry*
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology*