Oligometastases and oligo-recurrence: the new era of cancer therapy

Jpn J Clin Oncol. 2010 Feb;40(2):107-11. doi: 10.1093/jjco/hyp167. Epub 2010 Jan 4.


Recurrence or metastasis of cancer has been considered to occur in the last stage of the patient's life. However, the new notions of oligometastases and oligo-recurrence have been proposed and the paradigm shift in the conceptualization of cancer metastasis or cancer recurrence. Oligometastases is the state in which the patient shows distant relapse in only a limited number of regions. Local therapy such as surgery, radiotherapy and radiofrequency ablation for the relapsed sites could thus improve patient's survival. On the other hand, oligo-recurrence is a notion similar to oligometastases. However, the conditions of oligo-recurrence has a primary site of the cancer controlled, meaning that all gross recurrent or metastatic sites could be treated using local therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Combined Modality Therapy / trends
  • Humans
  • Neoplasm Metastasis / drug therapy*
  • Neoplasm Staging
  • Neoplasms / drug therapy*
  • Neoplasms / physiopathology*
  • Recurrence