A Breast-Fed Newborn With Megaloblastic Anemia-Treated With the Vitamin B12 Supplementation of the Mother

J Pediatr Hematol Oncol. 2009 Oct;31(10):763-5. doi: 10.1097/MPH.0b013e3181b7edb5.


Pregnant women with low B12 levels are unable to provide the necessary amount of this vitamin to their fetuses. The mothers are usually not anemic, and failure to thrive and neurologic deficits are more common in their infants than in megaloblastic anemia. We report the case of a newborn that was born to a vegetarian mother and presented with the symptoms of megaloblastic anemia at birth; we also discuss vitamin B12 metabolism during pregnancy and lactation. An interesting feature of the present case is that it is the only reported case of a newborn that was treated by supplementation of the mother.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Megaloblastic / drug therapy*
  • Breast Feeding*
  • Female
  • Humans
  • Infant, Newborn
  • Lactation
  • Mothers
  • Pregnancy
  • Treatment Outcome
  • Vitamin B 12 / therapeutic use*


  • Vitamin B 12