Systematic review: the effects of carbonated beverages on gastro-oesophageal reflux disease

Aliment Pharmacol Ther. 2010 Mar;31(6):607-14. doi: 10.1111/j.1365-2036.2010.04232.x. Epub 2010 Jan 4.


Background: Carbonated beverages have unique properties that may potentially exacerbate gastro-oesophageal reflux disease (GERD), such as high acidity and carbonation. Cessation of carbonated beverage consumption is commonly recommended as part of lifestyle modifications for patients with GERD.

Aims: To evaluate the relationship of carbonated beverages with oesophageal pH, oesophageal motility, oesophageal damage, GERD symptoms and GERD complications.

Methods: A systematic review.

Results: Carbonated beverage consumption results in a very short decline in intra-oesophageal pH. In addition, carbonated beverages may lead to a transient reduction in lower oesophageal sphincter basal pressure. There is no evidence that carbonated beverages directly cause oesophageal damage. Carbonated beverages have not been consistently shown to cause GERD-related symptoms. Furthermore, there is no evidence that these popular drinks lead to GERD complications or oesophageal cancer.

Conclusions: Based on the currently available literature, it appears that there is no direct evidence that carbonated beverages promote or exacerbate GERD.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Carbonated Beverages* / adverse effects
  • Gastric Emptying / physiology*
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / physiopathology
  • Humans
  • Manometry