Highly enantioselective Diels-Alder reactions of maleimides catalyzed by activated chiral oxazaborolidines

Santanu Mukherjee; E J Corey

doi:10.1021/ol902865d

Highly enantioselective Diels-Alder reactions of maleimides catalyzed by activated chiral oxazaborolidines

Org Lett. 2010 Feb 5;12(3):632-5. doi: 10.1021/ol902865d.

Authors

Santanu Mukherjee¹, E J Corey

Affiliation

¹ Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

PMID: 20063859
DOI: 10.1021/ol902865d

Abstract

Diels-Alder reactions of various combinations of maleimides and 1,3-dienes with cationic oxazaborolidines as catalysts have been shown to be highly efficient and enantioselective.

MeSH terms

Alkenes / chemistry*
Boron Compounds / chemistry*
Catalysis
Cyclization
Maleimides / chemistry*
Molecular Structure
Stereoisomerism

Substances

Alkenes
Boron Compounds
Maleimides