Tumor self-seeding: bidirectional flow of tumor cells

Cheuk T Leung; Joan S Brugge

doi:10.1016/j.cell.2009.12.013

Tumor self-seeding: bidirectional flow of tumor cells

Cell. 2009 Dec 24;139(7):1226-8. doi: 10.1016/j.cell.2009.12.013.

Authors

Cheuk T Leung¹, Joan S Brugge

Affiliation

¹ Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

PMID: 20064369
DOI: 10.1016/j.cell.2009.12.013

Abstract

Circulating tumor cells are responsible for seeding metastatic growth at distant sites. Kim et al. (2009) now discover that circulating tumor cells can reinfiltrate tumors at their primary organs and promote tumor progression.

MeSH terms

Animals
Disease Progression
Humans
Neoplasm Seeding*
Neoplasms / pathology*
Neoplasms / physiopathology
Neoplastic Cells, Circulating / pathology*