NetPath: a public resource of curated signal transduction pathways

Genome Biol. 2010 Jan 12;11(1):R3. doi: 10.1186/gb-2010-11-1-r3.


We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Access to Information
  • Animals
  • Apoptosis
  • Biochemistry / methods
  • Cell Movement
  • Computational Biology / methods*
  • Databases, Factual
  • Humans
  • Immune System
  • Interleukin-2 / metabolism
  • Models, Biological
  • Models, Genetic
  • Protein Interaction Mapping
  • Signal Transduction*
  • Software
  • Transcription, Genetic


  • Interleukin-2