Paternal alcohol consumption affects grooming response in rat offspring

Alcohol. Jan-Feb 1991;8(1):21-3. doi: 10.1016/0741-8329(91)91168-2.

Abstract

Grooming behavior in response to novelty and water immersion was examined in rat offspring sired by males consuming liquid alcohol diets containing 35%, 17.5% or 0% ethanol-derived calories (EDC). In the first study, offspring were tested at 35-38 days of age under conditions of lights on or off. Offspring in the 35% EDC group groomed less than controls. Lighting conditions did not affect grooming significantly. In the second study, animals were immersed in a water bath for 15 seconds and were then placed in the same observation chambers. As in the previous study, animals sired by alcohol-consuming fathers groomed considerably less than controls. These results were interpreted as suggesting offspring sired by alcohol-consuming fathers have a blunted response to conditions which spontaneously elicit behavior like grooming or ambulation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Dose-Response Relationship, Drug
  • Ethanol / toxicity*
  • Female
  • Fetus / drug effects*
  • Grooming / drug effects*
  • Male
  • Rats
  • Sex Factors

Substances

  • Ethanol