A method to diagnose opioid dependence resulting from heroin versus prescription opioids using the Composite International Diagnostic Interview

Contemp Clin Trials. 2010 Mar;31(2):185-8. doi: 10.1016/j.cct.2010.01.002. Epub 2010 Jan 14.


Treatment research with opioid-dependent populations has not traditionally distinguished between those dependent on prescription opioids versus dependent upon heroin. Evidence suggests there is a substantial subpopulation of individuals with opioid dependence resulting largely or exclusively from prescription opioid use. Because this subpopulation may respond to treatment differently from heroin users, a method for discriminating DSM-IV opioid dependence due to prescription opioid use would provide more precision when examining this population. This paper describes an innovative method using a currently available diagnostic instrument, to diagnose DSM-IV opioid dependence and distinguish between dependence resulting from prescription opioids versus dependence upon heroin.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Clinical Trials as Topic
  • Diagnosis, Differential
  • Diagnostic and Statistical Manual of Mental Disorders
  • Heroin Dependence / diagnosis*
  • Heroin*
  • Humans
  • Prescription Drugs*
  • Psychiatric Status Rating Scales


  • Prescription Drugs
  • Heroin