Vitamin B6: Killing two birds with one stone?

Phytochemistry. 2010 Apr;71(5-6):495-501. doi: 10.1016/j.phytochem.2009.12.015. Epub 2010 Jan 19.


Vitamin B6 comprises a group of compounds that are involved in a surprisingly high diversity of biochemical reactions. Actually, most of these reactions are co-catalyzed by a single B6 vitamer, pyridoxal 5'-phosphate, making it a crucial and versatile co-factor in many metabolic processes in the cell. In addition, it has been demonstrated in recent years that vitamin B6 has a second important function by being an effective antioxidant. Because of these two characteristics the vitamin is an interesting compound to study in plants. This review provides a brief overview and update on such important aspects like vitamin B6-dependent enzymes and known biosynthetic pathways in plants, phenotypes of plant mutants affected in vitamin B6 biosynthesis, and the potential benefits of modifying vitamin B6 content in plants.

Publication types

  • Review

MeSH terms

  • Antioxidants
  • Biosynthetic Pathways
  • Enzymes / metabolism
  • Genes, Plant
  • Homeostasis
  • Mutation
  • Phenotype
  • Plants / genetics
  • Plants / metabolism*
  • Pyridoxal Phosphate / biosynthesis
  • Pyridoxal Phosphate / genetics
  • Vitamin B 6 / biosynthesis*
  • Vitamin B 6 / genetics


  • Antioxidants
  • Enzymes
  • Pyridoxal Phosphate
  • Vitamin B 6