Cytogenetic analysis of a congenital fibrosarcoma

Cancer Genet Cytogenet. 1991 Mar;52(1):37-41. doi: 10.1016/0165-4608(91)90051-u.


Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, +11, +20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that may prove diagnostic for this tumor is beginning to emerge.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Fibrosarcoma / congenital*
  • Fibrosarcoma / genetics*
  • Humans
  • Infant, Newborn
  • Karyotyping
  • Leg*
  • Male
  • Soft Tissue Neoplasms / congenital*
  • Soft Tissue Neoplasms / genetics*