Therapy: nonhormonal treatment of hot flashes-a viable alternative?

Nat Rev Endocrinol. 2010 Feb;6(2):66-7. doi: 10.1038/nrendo.2009.269.

Abstract

A new study published in the Journal of Clinical Oncology has ascertained the efficacy of selective serotonin-reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors and gabapentin to decrease menopausal hot flashes. Are these nonhormonal treatment options a viable alternative to hormone replacement therapy?

Publication types

  • Comparative Study

MeSH terms

  • Adrenergic Uptake Inhibitors / adverse effects
  • Adrenergic Uptake Inhibitors / therapeutic use
  • Amines / adverse effects
  • Amines / therapeutic use*
  • Antidepressive Agents / therapeutic use*
  • Breast Neoplasms / drug therapy
  • Contraindications
  • Cyclohexanecarboxylic Acids / adverse effects
  • Cyclohexanecarboxylic Acids / therapeutic use*
  • Estrogen Replacement Therapy*
  • Female
  • Gabapentin
  • Hot Flashes / drug therapy*
  • Humans
  • Menopause*
  • Randomized Controlled Trials as Topic
  • Selective Serotonin Reuptake Inhibitors / adverse effects
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Tamoxifen / antagonists & inhibitors
  • gamma-Aminobutyric Acid / adverse effects
  • gamma-Aminobutyric Acid / therapeutic use*

Substances

  • Adrenergic Uptake Inhibitors
  • Amines
  • Antidepressive Agents
  • Cyclohexanecarboxylic Acids
  • Serotonin Uptake Inhibitors
  • Tamoxifen
  • gamma-Aminobutyric Acid
  • Gabapentin