Chloride channels of intracellular membranes

FEBS Lett. 2010 May 17;584(10):2102-11. doi: 10.1016/j.febslet.2010.01.037. Epub 2010 Jan 26.


Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Chloride Channels / metabolism*
  • Humans
  • Intracellular Membranes / metabolism*


  • Chloride Channels