Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
, 20 (4), 447-53

Fewer Nutrient Deficiencies After Laparoscopic Sleeve Gastrectomy (LSG) Than After Laparoscopic Roux-Y-gastric Bypass (LRYGB)-a Prospective Study

Affiliations
Clinical Trial

Fewer Nutrient Deficiencies After Laparoscopic Sleeve Gastrectomy (LSG) Than After Laparoscopic Roux-Y-gastric Bypass (LRYGB)-a Prospective Study

Simone Gehrer et al. Obes Surg.

Abstract

Background: Deficiencies in micronutrients after bariatric operations are frequent, despite routine supplementation. Main outcome measures were pre- and postoperative frequency of nutrient deficiencies and success rate of their treatment.

Methods: Between 5/2004 and 12/2006, 136 patients (m:f = 0:4) with an average body mass index of 45 (35-58) kg/m(2) and age of 53 (21-66) years were prospectively analysed. Laparoscopic Roux-Y-gastric bypass (LRYGB) was performed in 86 patients and laparoscopic sleeve gastrectomy (LSG) was performed in 50 patients. The patients were examined before surgery as well as 3, 6, 12, 24, 30, and 36 months postoperatively using a standard protocol including laboratory tests. The mean follow-up time was 24.4 (12-40) months; the follow-up rate was 100%.

Results: Prior to surgery, 57% of the patients had at least one deficiency, 23% of whom had vitamin D(3) deficiency. Frequent postoperative deficiencies after LSG were zinc, vitamin D(3), folic acid, iron, and vitamin B(12); after LRYGB, vitamin B(12), vitamin D(3), zinc, and secondary hyperparathyroidism. No vitamin B(1) or B(6) deficiencies were found. Calcium levels were normal in all patients. Treatment of the deficiencies was mostly successful.

Conclusion: Preoperatively, 57% of morbidly obese patients already had a deficiency. Postoperatively, significantly more vitamin B(12) and vitamin D deficiencies and hyperparathyroidism were found in patients who had undergone LRYGB. After LSG, folate deficiency was more frequent (but not significantly so). Calcium levels were normal in all patients; therefore, parathyroid hormone and vitamin D(3) levels are more sensitive markers for early detection of disorders of calcium metabolism. Iron deficiency anaemia is most efficiently treated by IV therapy.

Similar articles

See all similar articles

Cited by 95 PubMed Central articles

See all "Cited by" articles

References

    1. Am J Surg. 2002 Aug;184(2):103-13 - PubMed
    1. Obes Surg. 2004 Oct;14(9):1227-32 - PubMed
    1. Ann Intern Med. 2005 Apr 5;142(7):547-59 - PubMed
    1. J Gastrointest Surg. 2006 Jul-Aug;10(7):1033-7 - PubMed
    1. J Gastrointest Surg. 2005 Nov;9(8):1106-10; discussion 1110-1 - PubMed

Publication types

Feedback