Invited review: physiological properties of bioactive peptides obtained from whey proteins

J Dairy Sci. 2010 Feb;93(2):437-55. doi: 10.3168/jds.2009-2566.


Processing of whey proteins yields several bioactive peptides that can trigger physiological effects in the human body: on the nervous system via their opiate and ileum-contracting activities; on the cardiovascular system via their antithrombotic and antihypertensive activities; on the immune system via their antimicrobial and antiviral activities; and on the nutrition system via their digestibility and hypocholesterolemic effects. The specific physiological effects, as well the mechanisms by which they are achieved and the stabilities of the peptides obtained from various whey fractions during their gastrointestinal route, are specifically discussed in this review.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Milk Proteins / metabolism*
  • Nutritional Physiological Phenomena / physiology*
  • Peptides / chemistry
  • Peptides / metabolism
  • Peptides / physiology*
  • Protein Stability
  • Whey Proteins


  • Milk Proteins
  • Peptides
  • Whey Proteins