The role played by endogenous and exogenous electric fields in DNA signaling and repair

DNA Repair (Amst). 2010 Apr 4;9(4):356-7. doi: 10.1016/j.dnarep.2009.12.023. Epub 2010 Jan 27.

Abstract

Comments are made and new insights are provided on the key role played by endogenous and exogenous electric fields, where the former starts and conducts the repairing chain, while the latter is able to scramble the completion of the repair process and, as a consequence, may have important potential as a radiation sensitizer for clinical application.

Publication types

  • Letter

MeSH terms

  • DNA / chemistry
  • DNA / metabolism*
  • DNA Breaks, Double-Stranded
  • DNA Damage
  • DNA Repair*
  • Models, Biological
  • Radiation Dosage
  • Signal Transduction*

Substances

  • DNA