Improving the quality of 2D solid-state NMR spectra of microcrystalline proteins by covariance analysis

Chem Commun (Camb). 2010 Feb 14;46(6):952-4. doi: 10.1039/b920844e. Epub 2009 Dec 9.

Abstract

Gaining time, resolution and sensitivity at the same time: covariance processing of two-dimensional NMR spectra of microcrystalline proteins improves spectral quality over conventional Fourier transformation despite a significant reduction of the experimental time.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Fourier Analysis
  • Nuclear Magnetic Resonance, Biomolecular / methods*
  • Proteins / chemistry*

Substances

  • Proteins