Review
doi: 10.1016/j.hoc.2009.11.006.
Update on thalassemia: clinical care and complications
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- PMID: 20113904
- DOI: 10.1016/j.hoc.2009.11.006
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Review
Update on thalassemia: clinical care and complications
Hematol Oncol Clin North Am.
2010 Feb.
Abstract
beta-Thalassemia, originally named Cooley anemia, is an inherited blood disease. Various types of thalassemia are inherited anemias caused by mutations at the globin gene loci on chromosomes 16 and 11, affecting the production of alpha- or beta-globin protein, respectively. The combination of early diagnosis, improvements in monitoring for organ complications, and advances in supportive care have enabled many patients who have severe thalassemia syndromes to live productive, active lives well into adulthood.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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