Genetic analysis of 17 Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic minority group

Zhou Yi; Wang Jun; Song XingBo; Lu XiaoJun; Ding Liu; Ying BinWu

doi:10.1016/j.legalmed.2009.11.003

Genetic analysis of 17 Y-chromosomal STRs haplotypes of Chinese Tibetan ethnic minority group

Leg Med (Tokyo). 2010 Mar;12(2):108-11. doi: 10.1016/j.legalmed.2009.11.003. Epub 2010 Jan 29.

Authors

Zhou Yi¹, Wang Jun, Song XingBo, Lu XiaoJun, Ding Liu, Ying BinWu

Affiliation

¹ Division of Molecular Diagnosis, Department of Lab Medicine, West China Hospital, Sichuan University, Chengdu, PR China.

PMID: 20116321
DOI: 10.1016/j.legalmed.2009.11.003

Abstract

We have co-amplified and analyzed 17 Y-chromosomal STRs loci (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATA-H4 and DYS385a/b) in 132 healthy unrelated autochthonous male individuals of Chinese Tibetan ethnic group residing in Lassa area of China. The gene diversity values for the Y-STRs loci ranged from a minimum 0.206 for DYS391 locus to a maximum of 0.912 for DYS385a/b locus in the populations. A total of 123 haplotypes were identified, among which 115 were unique and 8 occurred more than once. The overall haplotype diversity for 17 Y-STRs loci was 0.998. Research results will be valuable for forensic use in the regions and for Chinese population genetic study.

MeSH terms

DNA Fingerprinting
Ethnicity / genetics*
Gene Frequency
Genes, Y-Linked*
Genetics, Population
Haplotypes*
Humans
Male
Polymorphism, Genetic
Tandem Repeat Sequences*
Tibet