[Diffuse stromal corneal opacity and alterations of the hands]

Ophthalmologe. 2010 Apr;107(4):363-5. doi: 10.1007/s00347-009-2066-2.
[Article in German]


Bilateral stromal corneal opacity is a differential diagnostic challenge for ophthalmologists. In this article 2 female patients aged 30 and 36 years old, respectively, with different degrees of expression of stromal diffuse corneal opacity will be presented. Patient 1 was of short stature (114 cm) and patient 2 was 172 cm in size. Both patients exhibited altered joint structures of the hands and feet and diffuse stromal corneal opacity. Furthermore, patient 1 had both mitral and aortal insufficiencies and patient 2 an aorta insufficiency. The stromal diffuse corneal opacity was indicative of Schleie syndrome. For patients with reduced vision a lamellary keratoplasty is to be recommended.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Abnormalities, Multiple / diagnosis*
  • Adult
  • Corneal Opacity / diagnosis*
  • Corneal Stroma / abnormalities*
  • Corneal Stroma / pathology*
  • Female
  • Foot Deformities, Congenital / diagnosis*
  • Hand Deformities, Congenital / diagnosis*
  • Humans