Krukenberg's tumour

Niger J Med. 2009 Oct-Dec;18(4):416-9. doi: 10.4314/njm.v18i4.51255.


Background: Krukenburg's tumour, a metastatic cancer to the ovary can pose difficulties in early diagnosis. The paucity of reports from our environment coupled with the difficulties we encountered makes it imperative that we report this case.

Methods: We present a 32-year-old lady who presented with mucoid and bloody diarrhoea associated with menstrual irregularity, weight loss and lower abdominal pains 2 years after surgical treatment for gastric cancer. Literature on Krukenburg's tumour was also reviewed.

Results: While serum level of CEA was found to be elevated and colonoscopy showed an ulcerated mass obliterating the lumen of the sigmoid colon, abdominal CT scan revealed bilateral adnexal masses. The histology of the colonic lesion showed signet ring carcinoma while the enlarged ovaries turned out to have evidence of metastatic adenocarcinoma.

Conclusion: Early diagnosis of KT can be difficult. Periodic surveillance is, therefore, essential especially in those who have had a gastrointestinal malignancy.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / secondary*
  • Adenocarcinoma / surgery
  • Adult
  • Carcinoma, Signet Ring Cell / diagnosis
  • Carcinoma, Signet Ring Cell / secondary*
  • Carcinoma, Signet Ring Cell / surgery
  • Colonic Neoplasms / diagnosis
  • Colonic Neoplasms / secondary*
  • Colonic Neoplasms / surgery
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Humans
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / secondary*
  • Ovarian Neoplasms / surgery
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery