Laparoscopic radical hysterectomy with the use of a modified uterine manipulator for the management of stage IB1 cervix cancer

J Obstet Gynaecol. 2010 Jan;30(1):49-52. doi: 10.3109/01443610903303039.


We prospectively collected data on all patients with stage IB1 cervical cancer, who underwent total laparoscopic radical hysterectomy with the use of a modified uterine manipulator. From January 2000 to December 2005, 54 patients met the study criteria. The mean age was 41.8 +/- 7.47 years. Average BMI (kg/m(2)) was 27.38 +/- 3.13. Squamous carcinoma and adenocarcinoma were found in 88.88% and 11.11% of the cases, respectively. The average surgical time was 265 +/- 70.8 min. The mean estimated blood loss was 276.11 +/- 123.03 ml. The average patient lymph node count was 19.64 +/- 5.08. Positive malignant lymph nodes were identified in 11.11% of the cases. Surgical margins were free of disease in all patients. The mean hospital stay was 1.5 +/- 1 days. There was no mortality. Total laparoscopic radical hysterectomy can be considered a safe alternative to laparotomy. The use of a uterine manipulator does not pose an increased surgical risk and allows for a simpler and more feasible procedure.

Publication types

  • Clinical Trial

MeSH terms

  • Adenocarcinoma / surgery*
  • Adult
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Hysterectomy, Vaginal / instrumentation*
  • Hysterectomy, Vaginal / methods
  • Laparoscopy / methods*
  • Middle Aged
  • Prospective Studies
  • Uterine Cervical Neoplasms / surgery*