Primary angiitis of the central nervous system: apparent diffusion coefficient lesion analysis

Clin Imaging. Jan-Feb 2010;34(1):1-6. doi: 10.1016/j.clinimag.2009.03.007.


Apparent diffusion coefficients (ADCs) of the brain lesions in primary angiitis of the central nervous system (PACNS) patients were analyzed in this study. The mean ADC ratios for acute/subacute phase lesions were significantly lower than that for chronic phase lesions. However, some acute/subacute phase lesions had elevated ADCs and these lesions disappeared overtime, implicating a nonischemic mechanism in PACNS.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Algorithms*
  • Brain / pathology*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Information Storage and Retrieval / methods*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Vasculitis, Central Nervous System / diagnosis*