So-called sclerosing hemangioma of lung: current concept

Ann Diagn Pathol. 2010 Feb;14(1):60-7. doi: 10.1016/j.anndiagpath.2009.07.002. Epub 2009 Dec 11.


Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features. Despite various patterns, there are 2 unifying cellular components: "surface cells" and "round cells." Although histogenesis has been debated for decades, most ultrastructural, immunocytochemical, and molecular studies strongly indicate a neoplastic epithelial derivation for both cellular components. Herein, we present a review of sclerosing hemangioma and summarize the essential data regarding histologic, cytologic, and ancillary findings of this distinctive pulmonary neoplasm.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism*
  • Humans
  • Immunohistochemistry
  • Pulmonary Sclerosing Hemangioma / genetics
  • Pulmonary Sclerosing Hemangioma / metabolism*
  • Pulmonary Sclerosing Hemangioma / pathology*


  • Biomarkers, Tumor