ADHD, learning, and academic performance in phenylketonuria

Mol Genet Metab. 2010;99 Suppl 1:S52-8. doi: 10.1016/j.ymgme.2009.09.013.


Despite having average intellectual abilities, academic difficulties are relatively common in children and adolescents with PKU. These academic difficulties may be a function of attention deficit hyperactivity disorder (ADHD), executive functioning deficits, and processing speed deficits, all of which are known to affect academic performance in non-PKU populations. This review focuses on what is currently known about academic performance in youth with PKU and offers suggestions for future research.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Attention Deficit Disorder with Hyperactivity / complications*
  • Child
  • Educational Status*
  • Executive Function
  • Female
  • Humans
  • Intelligence
  • Learning Disabilities / complications
  • Learning*
  • Male
  • Phenylketonurias / complications*