A meta-analytic review of the psychosocial adjustment of youth with inflammatory bowel disease

J Pediatr Psychol. 2010 Sep;35(8):857-69. doi: 10.1093/jpepsy/jsp120. Epub 2010 Feb 1.


Objective: To conduct a meta-analytic review of psychosocial adjustment of youth with inflammatory bowel disease (IBD).

Methods: Nineteen studies with a total of 1167 youth with IBD (M age = 14.33, 50% female) were included. Effect size (ES) estimates were calculated for anxiety symptoms & disorders, depressive symptoms & disorders, internalizing symptoms & disorders, externalizing symptoms, quality of life (QOL), social functioning, and self-esteem. Separate ESs were calculated for comparisons between IBD and youth with chronic illnesses versus healthy youth.

Results: Youth with IBD had higher rates of depressive disorders and internalizing disorders than youth with other chronic conditions. Youth with IBD had higher parent-reported internalizing symptoms, lower parent- and youth-reported QOL, and lower youth-reported social functioning compared to healthy youth.

Conclusions: Clinical attention to depressive disorders, QOL, and social functioning may be particularly salient in the context of pediatric IBD.

Publication types

  • Meta-Analysis
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adaptation, Psychological*
  • Adolescent
  • Anxiety / psychology
  • Anxiety Disorders / psychology
  • Child
  • Depression / psychology
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Inflammatory Bowel Diseases / psychology*
  • Male
  • Quality of Life / psychology*
  • Self Concept
  • Social Adjustment*