New mechanical recanalization devices - the future in pediatric stroke treatment?

J Invasive Cardiol. 2010 Feb;22(2):63-6.


Objective: To evaluate the recanalization rate and clinical outcome in children with acute ischemic stroke following treatment with innovative mechanical thrombectomy devices.

Patients and methods: Three subjects aged 7-16 years presenting with acute cerebral vascular occlusions (thrombolysis in myocardial infarction [TIMI] 0) were treated with either the Penumbra System, operating on an aspiration platform, or the Phenox clot retriever device, a flexible wire compound with perpendicularly-oriented polyamid microfilaments. Target vessels were the internal carotid artery, the middle cerebral artery and the basilar artery.

Results: Successful recanalization (TIMI 3) was attained in all cases. No device-related complications or intracranial hemorrhage occurred. Follow up was conducted for up to 30 days. A 10- to 26-point improvement in the National Institutes of Health Stroke Scale (NIHSS) score was achieved.

Conclusions: Mechanical thrombectomy devices possess a dual advantage whereby they can achieve instant recanalization as well as minimize the number of bleeds that customarily accompany intravenous and intra-arterial therapy. These new devices could contribute greatly to treatment decisions in a field not yet clearly defined by current guidelines.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Angiography, Digital Subtraction
  • Basilar Artery / diagnostic imaging
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / surgery*
  • Carotid Arteries / diagnostic imaging
  • Catheterization
  • Cerebral Angiography
  • Child
  • Female
  • Humans
  • Male
  • Stroke / diagnostic imaging
  • Stroke / surgery*
  • Thrombectomy / instrumentation*
  • Thrombectomy / methods
  • Thrombectomy / trends
  • Vacuum Curettage / instrumentation
  • Vacuum Curettage / methods
  • Vacuum Curettage / trends