Pharmacotherapy and other treatments for elderly patients with depression

J Clin Psychiatry. 2010 Jan;71(1):e03. doi: 10.4088/JCP.8001tx21c.


Depression in older adults can be difficult to diagnose and a challenge to treat. Clinicians must address treatment issues caused by aging, such as comorbid medical illness, physical limitations, or the presence of cognitive impairments. Proven treatments for depression in older adults include psychotherapy, medications, and electroconvulsive therapy. When choosing therapies for older patients, possible adverse side effects, drug interactions, and patient limitations should guide treatment selection.

MeSH terms

  • Aged
  • Aging
  • Antidepressive Agents / adverse effects
  • Antidepressive Agents / therapeutic use
  • Cognition Disorders / psychology
  • Depressive Disorder / drug therapy*
  • Depressive Disorder / psychology
  • Depressive Disorder / therapy
  • Electroconvulsive Therapy
  • Humans
  • Psychotherapy


  • Antidepressive Agents