Haplotype diversity of 17 Y-chromosomal STR loci in the Bangladeshi population

Shafiul Alam; Md Eunus Ali; Ahmad Ferdous; Tania Hossain; Md Mahamud Hasan; Sharif Akhteruzzaman

doi:10.1016/j.fsigen.2009.05.005

Haplotype diversity of 17 Y-chromosomal STR loci in the Bangladeshi population

Forensic Sci Int Genet. 2010 Feb;4(2):e59-60. doi: 10.1016/j.fsigen.2009.05.005. Epub 2009 Jun 21.

Authors

Shafiul Alam¹, Md Eunus Ali, Ahmad Ferdous, Tania Hossain, Md Mahamud Hasan, Sharif Akhteruzzaman

Affiliation

¹ Department of Forensic Medicine, Dhaka Medical College, Dhaka 1000, Bangladesh.

PMID: 20129457
DOI: 10.1016/j.fsigen.2009.05.005

Abstract

Haplotype and allele frequencies of 17 Y-chromosomal STR loci were determined in 216 unrelated Bangladeshi males. AmpFlSTR Y-filer PCR Amplification kit (Applied Biosystems) was used to type the following Y-STR markers: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438, DYS439, DYS437, DYS448, DYS458, DYS456, DYS635, and Y-GATA-H4. A total of 211 haplotypes for the 17 Y-STR markers were detected and, of these, 206 haplotypes were unique. The haplotype diversity was 0.9998, indicating a high potential for differentiating between male individuals in this population. Comparison analysis via Analysis of Molecular Variance (AMOVA) and construction of Neighbor Joining Tree revealed a close association of Bangladeshi population with Indian Gaddi and Southern Indian populations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Analysis of Variance
Asian People / genetics
Bangladesh
Chromosome Mapping
Chromosomes, Human, Pair 17* / genetics
Chromosomes, Human, Y*
Gene Amplification
Gene Frequency
Genetic Markers*
Genetic Variation
Genetics, Population*
Humans
India
Male
Polymerase Chain Reaction

Substances

Genetic Markers