Characterization of the highly discriminatory loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710

Forensic Sci Int Genet. 2010 Feb;4(2):104-10. doi: 10.1016/j.fsigen.2009.06.011. Epub 2009 Jul 29.

Abstract

During the study of genetic diversity at non-core Y-STRs in South African population groups, we identified loci with high discrimination capacity. In this study we present a detailed account of the allele diversity, allele sequence data, gene diversity, allele frequency spectrum and informativeness for assignment in the European English, Asian Indian and Xhosa population groups at loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS644 and DYS710. The suitability of these loci for forensic, genealogical and evolutionary studies is discussed, and nomenclature for loci DYS518, DYS612, DYS626 and DYS644 is suggested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • African Continental Ancestry Group / genetics
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Y / chemistry
  • Chromosomes, Human, Y / genetics*
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Primers
  • European Continental Ancestry Group / genetics
  • Evolution, Molecular
  • Genealogy and Heraldry
  • Genetic Variation
  • Genotype
  • Humans
  • India / ethnology
  • Male
  • Microsatellite Repeats / genetics*
  • Polymerase Chain Reaction
  • South Africa

Substances

  • DNA Primers
  • DNA