Evaluation of an upgraded version of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test for HIV-1 load quantification

J Clin Microbiol. 2010 Apr;48(4):1413-6. doi: 10.1128/JCM.01409-09. Epub 2010 Feb 3.


We evaluated the performance of the prototype Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, using prospective and archived clinical samples initially underquantitated by the Cobas AmpliPrep/Cobas TaqMan HIV-1 test. The performance of the new test was significantly improved, and the majority of the underquantitation observed with the first-version test was eliminated.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • HIV Infections / virology*
  • HIV-1 / genetics
  • HIV-1 / isolation & purification*
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Reagent Kits, Diagnostic*
  • Viral Load*


  • Reagent Kits, Diagnostic