Links between behavioral factors and inflammation

Clin Pharmacol Ther. 2010 Apr;87(4):479-82. doi: 10.1038/clpt.2009.255. Epub 2010 Feb 3.


This review focuses on the biobehavioral factors that show robust associations with markers of inflammation and discusses the following variables: diet, smoking, coffee, alcohol, exercise, and sleep disruption. Each of these variables has been assessed in large-scale epidemiological studies, and many of them have been assessed in clinical and experimental studies as well. Treatment strategies that target biobehavioral factors have the potential to complement and enhance the benefit of anti-inflammatory medicines.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alcohol Drinking / adverse effects
  • Coffee / adverse effects
  • Diet
  • Exercise
  • Health Behavior*
  • Humans
  • Inflammation / etiology
  • Inflammation / therapy*
  • Life Style*
  • Sleep Wake Disorders / complications
  • Smoking / adverse effects


  • Coffee