Prevalence of depression and anxiety disorders in HIV-positive outpatients in rural Tanzania

AIDS Care. 2010 Apr;22(4):415-9. doi: 10.1080/09540120903253981.


HIV/AIDS is associated with significant mental health morbidity in high-income countries, and depression associated with HIV/AIDS has been linked with faster disease progression and reduced drug adherence. However, research on mental health is scarce in sub-Saharan Africa where infection levels are highest. This cross-sectional study of 220 HIV-positive outpatients at a dedicated Tanzanian HIV/AIDS care centre assessed sociodemographics, clinical variables and prevalence of ICD-10 common mental health diagnoses via a standardised psychiatric questionnaire (the Clinical Interview Schedule-Revised). Depression or mixed anxiety and depression was identified in 15.5% of subjects, with 4.5% suffering from other anxiety disorders. This suggests routine HIV care in sub-Saharan Africa should include assessment and treatment of mental health issues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anxiety Disorders / epidemiology*
  • Anxiety Disorders / etiology
  • Cross-Sectional Studies
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / etiology
  • Female
  • HIV Infections / psychology*
  • Humans
  • Male
  • Middle Aged
  • Rural Population
  • Tanzania / epidemiology
  • Young Adult