Beans and diabetes: Phaseolus vulgaris preparations as antihyperglycemic agents

J Med Food. 2010 Apr;13(2):251-4. doi: 10.1089/jmf.2009.0002.


Bean pods (Phaseolus vulgaris) are among the most widely used traditional remedies against diabetes mellitus. Historical knowledge is summarized and compared to recent study results. Reports dating from the first half of the 20(th) century as well as recent publications show contradictory results. It seems that Phaseolus preparations should not be considered the first choice in phytopharmaceutical treatment of diabetes or lead structure research. To be effective, fairly high doses of aqueous extracts need to be given. Because of their fiber content and an alpha-amylase inhibitory effect, beans might be more useful as food components in preventing or ameliorating type 2 diabetes.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / diet therapy
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Dietary Fiber / adverse effects
  • Dietary Fiber / therapeutic use
  • Fruit
  • History, 20th Century
  • Humans
  • Hypoglycemic Agents / adverse effects
  • Hypoglycemic Agents / history
  • Hypoglycemic Agents / therapeutic use*
  • Phaseolus*
  • Plant Preparations / adverse effects
  • Plant Preparations / history
  • Plant Preparations / therapeutic use*
  • alpha-Amylases / antagonists & inhibitors


  • Dietary Fiber
  • Hypoglycemic Agents
  • Plant Preparations
  • alpha-Amylases