Abstract
In this prospective study 294 patients diagnosed with ectopic pregnancy (EP) were treated with multiple-dose methotrexate (MTX) to determine the conversion rate to surgery. We concluded that multiple-dose MTX treatment had a low success rate, and the success rate was not related to initial b-hCG value; it was more related to the size of gestational mass before treatment.
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
MeSH terms
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Abortifacient Agents, Nonsteroidal / administration & dosage
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Adult
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Embryo, Mammalian / pathology
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Fallopian Tubes / drug effects
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Fallopian Tubes / pathology
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Female
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Follow-Up Studies
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Gestational Age
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Gynecologic Surgical Procedures / statistics & numerical data*
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Humans
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Injections, Intramuscular
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Methotrexate / administration & dosage*
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Organ Size
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Pregnancy
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Pregnancy, Ectopic / drug therapy*
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Pregnancy, Ectopic / epidemiology
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Pregnancy, Ectopic / pathology
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Pregnancy, Ectopic / surgery*
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Treatment Failure
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Treatment Outcome
Substances
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Abortifacient Agents, Nonsteroidal
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Methotrexate