Review
doi: 10.1016/j.febslet.2010.02.001.
Epub 2010 Feb 5.
Current knowledge of the pre-autophagosomal structure (PAS)
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- PMID: 20138172
- DOI: 10.1016/j.febslet.2010.02.001
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Review
Current knowledge of the pre-autophagosomal structure (PAS)
FEBS Lett.
.
Free article
Abstract
Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells.
Copyright 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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