Results of treatment of persistent hyperplastic primary vitreous

Ophthalmic Surg. 1991 Jan;22(1):48-52.


The records of 48 patients with persistent hyperplastic primary vitreous (PHPV) were reviewed. Approximately 17% had vision of 20/100 or better after surgery, contact lens fitting, and amblyopia therapy. Only eyes with a purely anterior presentation had successful visual outcomes. Lensectomy alone prevented glaucoma, but a membranectomy as well was required to ensure a successful visual result. Eyes with a posterior PHPV had poor visual results because of posterior pole abnormalities. I recommend that an attempt be made to visually salvage eyes with an anterior presentation. Eyes with a posterior or a combination anterior-posterior PHPV can be successfully treated for glaucoma, but the visual results will be poor.

Publication types

  • Case Reports

MeSH terms

  • Amblyopia / therapy
  • Cataract Extraction
  • Child, Preschool
  • Contact Lenses
  • Eye Diseases / surgery
  • Female
  • Glaucoma / prevention & control
  • Glaucoma / surgery
  • Humans
  • Hyperplasia
  • Infant
  • Infant, Newborn
  • Intraocular Pressure
  • Lens, Crystalline / surgery
  • Male
  • Prognosis
  • Visual Acuity
  • Vitrectomy
  • Vitreous Body / pathology
  • Vitreous Body / surgery*