[Experimental rationale for the use of enterosorbents in acute ethanol intoxication]

Patol Fiziol Eksp Ter. 2009 Oct-Dec;(4):29-30.
[Article in Russian]

Abstract

The experiment on 83 rats has provided a rationale for the use of enterosorbents in acute ethanol intoxication. Polysorb reduces the halflife of ethanol, recovers physical fitness in the animals with acute poisoning. The enterosorbents polysorb, litovit, and sapropel have been found to have a corrective effect on the level of the major plasma antioxidant ceruloplasmin in acute ethanol intoxication. Enterosorbents are an effective detoxifying agent in this condition. Examining the mechanisms of toxic action of ethanol allows the most expedient treatment policy to be substantiated in acute poisonings.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Alcoholic Intoxication / blood
  • Alcoholic Intoxication / therapy*
  • Animals
  • Benzopyrans / pharmacology*
  • Ceruloplasmin / metabolism
  • Enterosorption / methods*
  • Ethanol / adverse effects*
  • Ethanol / pharmacology
  • Humic Substances
  • Rats

Substances

  • Benzopyrans
  • Humic Substances
  • Ethanol
  • sapropel
  • Ceruloplasmin