A facile and mild synthesis of enamides using a gold-catalyzed nucleophilic addition to allenamides

Org Lett. 2010 Mar 5;12(5):1128-31. doi: 10.1021/ol1001494.

Abstract

A mild and facile synthesis of enamides has been developed, based on nucleophilic addition of electron-rich aromatic and heteroaromatics to an allenamide unit catalyzed by a gold salt. Yields for the transformation were 29-98%.