Methods in Mammalian Autophagy Research

Cell. 2010 Feb 5;140(3):313-26. doi: 10.1016/j.cell.2010.01.028.

Abstract

Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autophagy*
  • Cytological Techniques*
  • Humans
  • Phagosomes / metabolism